Hyperadrenocorticism (Cushing's syndrome)(HAC)
Also known as: Cushing's Disease · Cushing-Syndrom · Hyperadrenokortizismus · Morbus Cushing · Canine Hyperadrenocorticism · …
Overview
What it is
Cushing's syndrome is a hormonal disorder affecting the endocrine system, where the adrenal glands chronically produce too much of the stress hormone cortisol. This overproduction disrupts the dog's normal metabolism, fluid balance, and immune system function. It is typically caused by a benign tumor in either the pituitary gland or the adrenal glands themselves.
How it presents
Owners usually notice symptoms in middle-aged to older dogs, including excessive thirst and urination, a significantly increased appetite, and a sagging, pot-bellied abdomen. Other common signs include symmetrical hair loss, thin skin, and frequent panting or lethargy.
Treatment
While the condition is generally lifelong and cannot be cured, it can be successfully managed with daily medication and regular veterinary monitoring. The lifetime cost of treatment and diagnostic testing typically ranges from 3,000 to 12,000 EUR.
How it's tested
Low-Dose-Dexamethason-Suppressionstest(LDDST)
Primary testClinical examDer Low-Dose-Dexamethason-Suppressionstest (LDDST) ist der primäre klinische Funktionstest zur Diagnose des Cushing-Syndroms durch Messung der Cortisol-Suppression.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Hyperadrenocorticism (Cushing's syndrome)?
Cushing's syndrome is a hormonal disorder affecting the endocrine system, where the adrenal glands chronically produce too much of the stress hormone cortisol. This overproduction disrupts the dog's normal metabolism, fluid balance, and immune system function. It is typically caused by a benign tumor in either the pituitary gland or the adrenal glands themselves.
How is Hyperadrenocorticism (Cushing's syndrome) tested?
Tests currently in our database: Low-Dose-Dexamethason-Suppressionstest.
Which breeds are most affected?
Most commonly affected: Yorkshire Terrier, Boston Terrier, Boxer.