Histiocytic ulcerative colitis(HUC)
Also known as: Boxer colitis · Granulomatous colitis · Histiozytäre ulzerative Kolitis · Granulomatöse Kolitis · Granulomatous colitis of Boxer dogs · …
Overview
What it is
Histiocytic ulcerative colitis is a severe, chronic inflammatory disease of the large intestine, or colon. It occurs when specific bacteria invade the lining of the intestinal wall, triggering an abnormal and intense immune response. This leads to deep inflammation and painful ulcers in the colon.
How it presents
Symptoms typically appear in young dogs under two years of age. Owners will usually notice frequent, painful straining to defecate, weight loss, and diarrhea that often contains blood or mucus.
Treatment
The condition is highly treatable using targeted antibiotics and specialized diets, though it requires a precise diagnosis via colonoscopy and biopsy with FISH analysis. Total costs for diagnosis and treatment typically range from 1,500 to 6,000 EUR.
How it's tested
Koloskopie mit Biopsie und FISH-Analyse(Koloskopie/Biopsie)
Primary testClinical examDie Diagnose erfolgt über eine Koloskopie mit Entnahme von Gewebeproben (Biopsie) und anschließender histopathologischer Untersuchung sowie FISH-Analyse zum Nachweis von intrazellulären Escherichia coli.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
2 of 2 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Histiocytic ulcerative colitis?
Histiocytic ulcerative colitis is a severe, chronic inflammatory disease of the large intestine, or colon. It occurs when specific bacteria invade the lining of the intestinal wall, triggering an abnormal and intense immune response. This leads to deep inflammation and painful ulcers in the colon.
How is Histiocytic ulcerative colitis tested?
Tests currently in our database: Koloskopie mit Biopsie und FISH-Analyse.
Which breeds are most affected?
Most commonly affected: French Bulldog, Boxer.