Height, HMGA2-associated body-size variation
Also known as: HMGA2 locus · HMGA2 body size variant · HMGA2-associated dwarfism · Körpergrößen-Gen HMGA2 · Dog height gene variant
Overview
What it is
This is a natural genetic variation rather than a disease, affecting the skeletal system and overall body development. The HMGA2 gene plays a key role in regulating cell growth and division during development, which directly influences a dog's final skeletal height at the shoulders. Because this is a normal physical trait, it does not cause any underlying organ dysfunction or health issues.
How it presents
Owners will simply notice that their dog grows to a genetically determined smaller or larger adult size. This variation in height becomes fully apparent once the dog reaches skeletal maturity, typically between 9 and 18 months of age.
Treatment
Because this variation is a normal physical characteristic and not a medical condition, no treatment is required. There are no associated medical costs, resulting in a lifetime treatment cost of 0 EUR.
How it's tested
HMGA2-Genvariations-Test (Körpergröße)(HMGA2)
Primary testDNA testEin Gentest analysiert die Variation im HMGA2-Gen, um genetische Einflüsse auf die Körpergröße und Schulterhöhe des Hundes zu bestimmen.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Height, HMGA2-associated body-size variation?
This is a natural genetic variation rather than a disease, affecting the skeletal system and overall body development. The HMGA2 gene plays a key role in regulating cell growth and division during development, which directly influences a dog's final skeletal height at the shoulders. Because this is a normal physical trait, it does not cause any underlying organ dysfunction or health issues.
How is Height, HMGA2-associated body-size variation tested?
Tests currently in our database: HMGA2-Genvariations-Test (Körpergröße).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.