Hemophilia B(HEMB)
Also known as: Hämophilie B · Factor IX deficiency · Faktor-IX-Mangel · Christmas disease · Canine Hemophilia B · …
Overview
What it is
Haemophilia B is a severe, X-linked genetic bleeding disorder affecting the blood circulatory system. It is caused by a deficiency in clotting factor IX, which is a specific protein necessary for blood to clot properly. Without enough of this protein, the normal clotting process fails, leading to prolonged or uncontrolled bleeding.
How it presents
Symptoms typically appear during puppyhood. Owners may notice spontaneous bruising, bleeding gums, prolonged bleeding from minor injuries, or painful joint swelling caused by internal bleeding.
Treatment
The condition is incurable and requires lifelong management, including emergency blood or plasma transfusions to control bleeding. These supportive treatments are costly, with lifetime veterinary expenses typically ranging from 2,000 to 12,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Hämophilie B DNA-Test(HEMB)
Primary testDNA testDer DNA-Test identifiziert Mutationen im F9-Gen, die zu einem Mangel an Gerinnungsfaktor IX führen, und ermöglicht den Nachweis von betroffenen Hunden sowie symptomfreien Trägern.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Hämophilie B DNA-Test(F9)
Primary testDNA testEin DNA-Test zum Nachweis von Mutationen im F9-Gen, die zu einem Mangel an Gerinnungsfaktor IX und somit zu Hämophilie B führen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Hemophilia B?
Haemophilia B is a severe, X-linked genetic bleeding disorder affecting the blood circulatory system. It is caused by a deficiency in clotting factor IX, which is a specific protein necessary for blood to clot properly. Without enough of this protein, the normal clotting process fails, leading to prolonged or uncontrolled bleeding.
How is Hemophilia B tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Hämophilie B DNA-Test, Hämophilie B DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: English Coonhound.