Glycogen Storage Disease type IIIa (Curly Coated Retriever)(GSD IIIa)
Also known as: Glycogen Storage Disease Type IIIa · Cori's Disease · Forbes Disease · Glykogenose Typ IIIa · Glycogen Debranching Enzyme Deficiency · …
Overview
What it is
Glycogen Storage Disease Type IIIa is an inherited metabolic disorder where the body lacks a key enzyme needed to break down glycogen, which is a stored form of sugar used for energy. Without this enzyme, glycogen builds up to harmful levels in the liver and muscle tissues. This accumulation progressively damages these organs and prevents them from functioning properly.
How it presents
Symptoms typically appear in puppies or young dogs. Owners will usually notice severe muscle weakness, rapid tiring during exercise, general lethargy, and episodes of low blood sugar, which can cause wobbliness or collapse.
Treatment
This condition is incurable and requires lifelong management, including a specialized high-protein diet and regular veterinary monitoring. Lifetime care and support typically cost between 3,000 and 10,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Glykogenspeicherkrankheit Typ IIIa (GSD IIIa) DNA-Test(GSD IIIa)
Primary testDNA testEin DNA-Test zum Nachweis der Mutation im AGL-Gen, die fuer die Glykogenspeicherkrankheit Typ IIIa verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Glycogen Storage Disease type IIIa (Curly Coated Retriever)?
Glycogen Storage Disease Type IIIa is an inherited metabolic disorder where the body lacks a key enzyme needed to break down glycogen, which is a stored form of sugar used for energy. Without this enzyme, glycogen builds up to harmful levels in the liver and muscle tissues. This accumulation progressively damages these organs and prevents them from functioning properly.
How is Glycogen Storage Disease type IIIa (Curly Coated Retriever) tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Glykogenspeicherkrankheit Typ IIIa (GSD IIIa) DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Curly Coated Retriever.