Glomerulonephropathy(GN)
Also known as: Glomerulonephritis · Glomerulopathy · Protein-Losing Nephropathy · PLN · Hereditary Nephropathy · …
Overview
What it is
Glomerulonephropathy is a disease affecting the kidneys, specifically damaging the glomeruli, which are the tiny filtering units responsible for cleaning waste from the blood. When these filters are damaged, they fail to keep important proteins in the bloodstream, allowing them to leak out into the urine. This loss of protein can lead to wider complications throughout the body.
How it presents
Owners typically notice symptoms in young to middle-aged adult dogs, which may include increased drinking and urination, weight loss, and general sluggishness. Some dogs may also develop visible swelling or fluid retention in their limbs or abdomen.
Treatment
While the condition is chronic and cannot be cured, it can be managed long-term with a specialized diet and daily medications to support kidney function. Lifelong treatment is required, with estimated costs ranging from 3,000 to 12,000 EUR.
How it's tested
Urin-Protein-Kreatinin-Verhältnis(UPC)
Primary testClinical examDer UPC-Test bestimmt das Verhältnis von Protein zu Kreatinin im Urin, um einen abnormalen Proteinverlust über die Nieren (Proteinurie) als Zeichen einer Glomerulonephropathie nachzuweisen.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Klinische und labordiagnostische Nierenuntersuchung(Nierenprofil)
Primary testClinical examDie Diagnose einer Nephritis erfolgt klinisch durch Blutuntersuchungen (wie SDMA, Kreatinin, Harnstoff), Urinanalysen (Protein-Kreatinin-Verhältnis) und bildgebende Verfahren wie Ultraschall.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Klinische Laboruntersuchung (Urin- und Blutanalysen)(UPC & Blutprofil)
Primary testClinical examDie Diagnose des nephrotischen Syndroms erfolgt klinisch durch den Nachweis einer schweren Proteinausscheidung im Urin (UPC-Verhältnis) sowie einer Hypoalbuminämie und Hypercholesterinämie im Blutbild.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Glomerulonephropathy?
Glomerulonephropathy is a disease affecting the kidneys, specifically damaging the glomeruli, which are the tiny filtering units responsible for cleaning waste from the blood. When these filters are damaged, they fail to keep important proteins in the bloodstream, allowing them to leak out into the urine. This loss of protein can lead to wider complications throughout the body.
How is Glomerulonephropathy tested?
Tests currently in our database: Urin-Protein-Kreatinin-Verhältnis, Klinische und labordiagnostische Nierenuntersuchung, Klinische Laboruntersuchung (Urin- und Blutanalysen).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.