Glanzmann's Thrombasthenia (Otterhound)(GT)
Also known as: Glanzmann's Thrombasthenia · Glanzmann-Thrombasthenie · Thrombasthenie Typ Glanzmann · Platelet Glycoprotein IIb/IIIa Deficiency · Thrombasthenie beim Otterhound · …
Overview
What it is
Glanzmann's thrombasthenia is an inherited blood disorder that affects the circulatory system, specifically how blood clots. In affected dogs, a genetic defect prevents platelets (the blood cells responsible for stopping bleeding) from sticking together to form a plug. This means that even minor injuries can lead to severe, difficult-to-control bleeding because the body's natural clotting mechanism is impaired.
How it presents
Symptoms typically become noticeable in puppyhood, often during teething or after minor play. Owners may observe spontaneous nosebleeds, bleeding gums, unexplained bruising on the skin, or prolonged bleeding from minor cuts.
Treatment
This is an incurable, lifelong condition that requires careful management to prevent injury. Emergency veterinary care, including blood or platelet transfusions, is often needed for bleeding episodes, with lifetime costs typically ranging from 1,500 to 8,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Glanzmann's Thrombasthenia (Otterhound)?
Glanzmann's thrombasthenia is an inherited blood disorder that affects the circulatory system, specifically how blood clots. In affected dogs, a genetic defect prevents platelets (the blood cells responsible for stopping bleeding) from sticking together to form a plug. This means that even minor injuries can lead to severe, difficult-to-control bleeding because the body's natural clotting mechanism is impaired.
How is Glanzmann's Thrombasthenia (Otterhound) tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: American Foxhound.