Fucosidosis(FUCO)
Also known as: Canine Fucosidosis · Alpha-L-fucosidase deficiency · Lysosomale Speicherkrankheit · Alpha-Fucosidosis · Fukosidose · …
Overview
What it is
Fucosidosis is an inherited lysosomal storage disease, which means the dog's body lacks a specific enzyme needed to break down certain complex sugars. Without this enzyme, these sugars build up to toxic levels inside cells, causing severe and progressive damage to tissues, particularly the brain and nervous system.
How it presents
Owners typically notice symptoms starting between 1 and 2 years of age, including a loss of coordination, behavioral changes, vision loss, and difficulty swallowing. These signs gradually and steadily worsen over time.
Treatment
There is no cure for this condition, and care is focused entirely on keeping the dog comfortable. Palliative and supportive care over the course of the disease typically costs between 1,000 and 3,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Alpha-Fucosidose DNA-Test(FUCO)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis der Mutation im FUCA1-Gen, die für den Mangel an Alpha-L-Fucosidase verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Fucosidosis?
Fucosidosis is an inherited lysosomal storage disease, which means the dog's body lacks a specific enzyme needed to break down certain complex sugars. Without this enzyme, these sugars build up to toxic levels inside cells, causing severe and progressive damage to tissues, particularly the brain and nervous system.
How is Fucosidosis tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Alpha-Fucosidose DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: English Springer Spaniel.