Coat colour, grizzle(Eg)
Also known as: Grizzle · Domino · Grizzle coat color · Afghan grizzle · Saluki grizzle · …
Overview
What it is
Grizzle, also known as domino, is a harmless coat color pattern affecting the hair and skin pigment system, most commonly seen in sighthounds. It is inherited through a complex genetic process called multi-locus epistasis, meaning it requires a specific interaction between multiple genes—specifically MC1R, ASIP, and DEFB103—to express the pattern. This interaction regulates how dark and light pigments are distributed throughout the dog's coat.
How it presents
Owners will notice a distinctive light-colored facial mask paired with a darker saddle or body coat. This purely visual pattern is visible from birth or early puppyhood and has no impact on the dog's physical health.
Treatment
As this is a natural color variation and not a disease, no medical treatment is required. There are no associated veterinary costs, making the lifetime treatment cost 0 EUR.
How it's tested
MC1R-Genotypisierung (Eg-Lokus)(Eg-Lokus)
Primary testDNA testDer DNA-Test analysiert das MC1R-Gen auf die spezifische Eg-Variante, um das genetische Potenzial für das Grizzle- oder Domino-Farbmuster nachzuweisen.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Coat colour, grizzle?
Grizzle, also known as domino, is a harmless coat color pattern affecting the hair and skin pigment system, most commonly seen in sighthounds. It is inherited through a complex genetic process called multi-locus epistasis, meaning it requires a specific interaction between multiple genes—specifically MC1R, ASIP, and DEFB103—to express the pattern. This interaction regulates how dark and light pigments are distributed throughout the dog's coat.
How is Coat colour, grizzle tested?
Tests currently in our database: MC1R-Genotypisierung (Eg-Lokus).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.