Factor XI deficiency(FXID)
Also known as: Faktor-XI-Mangel · F11 deficiency · Plasma thromboplastin antecedent deficiency · PTA deficiency
Overview
What it is
Factor XI deficiency is an inherited blood clotting disorder affecting the circulatory system. It occurs when the body does not produce enough Factor XI, which is a specific protein crucial for helping the blood clot properly. Without enough of this protein, the normal chemical chain reaction that stops bleeding is disrupted.
How it presents
Affected dogs typically show no symptoms in their daily lives, but they may experience prolonged or severe bleeding after an injury, surgery, or dental procedure. This abnormal bleeding can become apparent at any age when a trauma or medical procedure occurs.
Treatment
While the underlying genetic condition cannot be cured, it is manageable by taking precautions, such as administering blood plasma transfusions before any planned surgeries. Treatment is typically only needed during these specific medical events, with costs ranging from 500 to 3000 EUR.
How it's tested
Faktor-XI-Defizienz DNA-Test(FXID)
Primary testDNA testEin Gentest zum Nachweis der Mutation im F11-Gen, die für den Mangel an Blutgerinnungsfaktor XI verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Factor XI deficiency?
Factor XI deficiency is an inherited blood clotting disorder affecting the circulatory system. It occurs when the body does not produce enough Factor XI, which is a specific protein crucial for helping the blood clot properly. Without enough of this protein, the normal chemical chain reaction that stops bleeding is disrupted.
How is Factor XI deficiency tested?
Tests currently in our database: Faktor-XI-Defizienz DNA-Test.
Which breeds are most affected?
Most commonly affected: Petit Bleu de Gascogne.