Paroxysmal Dyskinesia, SOD1-related
Also known as: SOD1-related paroxysmal dyskinesia · Paroxysmale Dyskinesie (SOD1) · SOD1-associated dyskinesia · Familial paroxysmal dyskinesia SOD1 · SOD1-PD
Overview
What it is
This is an inherited neurological disorder affecting the nervous system, caused by a specific mutation in the SOD1 gene. It leads to temporary disruptions in the brain's motor control centers, resulting in sudden episodes of involuntary muscle movements. Between these episodes, the dog's nervous system functions normally and they appear completely healthy.
How it presents
Owners will notice sudden, involuntary muscle spasms or abnormal limb movements that can last from minutes to hours, during which the dog remains fully conscious. These episodes typically begin during puppyhood or young adulthood and are often triggered by excitement or stress.
Treatment
While there is no cure, the condition is manageable through stress reduction, dietary changes, or lifelong neurological medications. Management and diagnostic monitoring typically cost between 250 and 1000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Paroxysmal Dyskinesia, SOD1-related?
This is an inherited neurological disorder affecting the nervous system, caused by a specific mutation in the SOD1 gene. It leads to temporary disruptions in the brain's motor control centers, resulting in sudden episodes of involuntary muscle movements. Between these episodes, the dog's nervous system functions normally and they appear completely healthy.
How is Paroxysmal Dyskinesia, SOD1-related tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.