Distal sensorimotor polyneuropathy(DSPN)
Also known as: Distale sensorimotorische Polyneuropathie · Hereditäre Polyneuropathie · Canine inherited polyneuropathy · Polyneuropathy, distal sensorimotor
Overview
What it is
This is an inherited disorder of the nervous system where the peripheral nerves—the communication lines connecting the brain and spinal cord to the rest of the body—gradually deteriorate. This damage primarily affects the limbs, disrupting the signals needed for proper muscle movement and sensory feedback. Because the exact genetic mutation is currently unknown, diagnosis relies on clinical exams, nerve function tests, and tissue biopsies rather than a DNA test.
How it presents
Symptoms typically appear within the first year of life, starting as weakness and coordination issues in the hind legs. Owners may notice muscle wasting, a dragging gait, and a reduced sensitivity to touch or pain in the dog's paws.
Treatment
There is no cure for this progressive condition, but supportive care, physical therapy, and mobility aids can help manage symptoms. Lifelong management typically costs between €2,000 and €7,000.
How it's tested
Neurologische und elektrodiagnostische Untersuchung(DSPN-Klinik)
Primary testClinical examDie Diagnose erfolgt durch eine umfassende neurologische Untersuchung, Elektrodiagnostik (Messung der Nervenleitgeschwindigkeit und Elektromyographie) sowie gegebenenfalls eine Nerven- und Muskelbiopsie.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Distal sensorimotor polyneuropathy?
This is an inherited disorder of the nervous system where the peripheral nerves—the communication lines connecting the brain and spinal cord to the rest of the body—gradually deteriorate. This damage primarily affects the limbs, disrupting the signals needed for proper muscle movement and sensory feedback. Because the exact genetic mutation is currently unknown, diagnosis relies on clinical exams, nerve function tests, and tissue biopsies rather than a DNA test.
How is Distal sensorimotor polyneuropathy tested?
Tests currently in our database: Neurologische und elektrodiagnostische Untersuchung.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.