Dilated Cardiomyopathy (DCM), LMNA-related(DCM)
Also known as: Dilated Cardiomyopathy LMNA-related · LMNA-DCM · Dilatative Kardiomyopathie LMNA-Typ · Lamin A/C Kardiomyopathie · LMNA dilated cardiomyopathy · …
Overview
What it is
This is an inherited heart disease where the heart muscle becomes weak and the heart chambers stretch and enlarge, a process known as dilation. Because the muscle is weakened, the heart cannot pump blood efficiently to the rest of the body, leading to reduced oxygen delivery. This condition is caused by a genetic mutation affecting the structural support of the heart cells.
How it presents
Symptoms typically appear in middle to advanced age. Owners may notice their dog tiring quickly during exercise, coughing, having difficulty breathing, or experiencing sudden fainting spells.
Treatment
The disease is progressive and incurable, but symptoms can be managed with lifelong cardiac medications and supportive care. Lifetime treatment and monitoring typically cost between €2,000 and €8,000.
How it's tested
Herzultraschall (Echokardiographie)(Herz-Echo)
Primary testCardiac examEchokardiographie zur Beurteilung von Herzklappen, -wänden, -funktion. Pflicht z.B. bei Cavalier King Charles Spaniel (MMVD).
Issuing body: vet
Result scheme: Cardiac-OFA
DCM DNA-Test (Dilatative Kardiomyopathie)(DCM)
DNA testDCM-assoziierte Mutation (z.B. PDK4 bei Dobermann). Mehrere Mutationen je nach Rasse.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Dilated Cardiomyopathy (DCM), LMNA-related?
This is an inherited heart disease where the heart muscle becomes weak and the heart chambers stretch and enlarge, a process known as dilation. Because the muscle is weakened, the heart cannot pump blood efficiently to the rest of the body, leading to reduced oxygen delivery. This condition is caused by a genetic mutation affecting the structural support of the heart cells.
How is Dilated Cardiomyopathy (DCM), LMNA-related tested?
Tests currently in our database: Herzultraschall (Echokardiographie), DCM DNA-Test (Dilatative Kardiomyopathie), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.