Diffuse cystic renal dysplasia and hepatic fibrosis(RDHN)
Also known as: Cystic renal dysplasia and hepatic fibrosis · Hepatorenal fibrocystic disease · Juvenile renal dysplasia and hepatic fibrosis · Renal-hepatic dysplasia · Cystic glomerular disease and hepatic fibrosis · …
Overview
What it is
This inherited condition, known as RDHN, causes severe maldevelopment of both the kidneys and the liver. It leads to the formation of fluid-filled sacs (cysts) in the kidneys and progressive scarring (fibrosis) in the liver tissue. These structural defects prevent both vital organ systems from functioning.
How it presents
Because this is a lethal neonatal disease, affected puppies are typically stillborn or die within the first few days of life. Signs in newborns include extreme weakness, failure to nurse, and rapid decline.
Treatment
This condition is untreatable and unfortunately fatal shortly after birth. Veterinary costs are generally limited to supportive care or humane euthanasia, ranging from 0 to 500 EUR.
How it's tested
Abdominalsonographie(Ultraschall)
Primary testUltrasoundDie Diagnose von Eierstockzysten erfolgt mittels einer Ultraschalluntersuchung (Sonographie) des Abdomens, bei der die flüssigkeitsgefüllten Strukturen an den Ovarien dargestellt werden.
Issuing body: vet
Result scheme: Cardiac-OFA
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Diffuse cystic renal dysplasia and hepatic fibrosis?
This inherited condition, known as RDHN, causes severe maldevelopment of both the kidneys and the liver. It leads to the formation of fluid-filled sacs (cysts) in the kidneys and progressive scarring (fibrosis) in the liver tissue. These structural defects prevent both vital organ systems from functioning.
How is Diffuse cystic renal dysplasia and hepatic fibrosis tested?
Tests currently in our database: Abdominalsonographie, Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.