Cystinuria, type II-B
Also known as: Cystinuria Type II-B · Cystinurie Typ II-B · SLC7A9 Cystinuria · Cystine Urolithiasis Type II-B · Dominant Cystinuria · …
Overview
What it is
This is an inherited metabolic disorder affecting the kidneys, where the kidneys fail to reabsorb the amino acid cystine, a protein building block, from the urine. Because the cystine is not properly filtered, it accumulates in the urinary tract and clumps together. This leads to the formation of painful crystalline deposits and stones in the bladder or kidneys.
How it presents
Owners may notice blood in the urine, frequent straining to urinate, or recurrent urinary tract infections, typically starting in young to middle-aged dogs. Male dogs are at a higher risk of developing a complete, life-threatening blockage of the urethra.
Treatment
While the underlying condition is lifelong and incurable, it is manageable with a specialized diet and regular veterinary monitoring. If a blockage occurs, emergency surgery is required to remove the stones, with overall treatment costs typically ranging from 1,500 to 7,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Cystinuria, type II-B?
This is an inherited metabolic disorder affecting the kidneys, where the kidneys fail to reabsorb the amino acid cystine, a protein building block, from the urine. Because the cystine is not properly filtered, it accumulates in the urinary tract and clumps together. This leads to the formation of painful crystalline deposits and stones in the bladder or kidneys.
How is Cystinuria, type II-B tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.