Cleft palate 1, DLX6-related(CP1)
Also known as: Cleft Palate 1 · DLX6-related cleft palate · Gaumenspalte Typ 1 · Congenital cleft palate
Overview
What it is
This is a congenital birth defect affecting the skeletal and digestive systems where the roof of the mouth, known as the palate, fails to fuse properly during embryonic development. This failure leaves an abnormal opening, formally called palatoschisis, that connects the oral cavity directly to the nasal passages. Because of this opening, food and liquids can easily pass from the mouth into the respiratory tract.
How it presents
Symptoms are visible immediately after birth in newborn puppies. Owners will typically notice difficulty nursing, milk dripping from the nose during feeding, and coughing or gagging.
Treatment
The condition is treatable through surgical reconstruction of the palate, though it often requires multiple procedures and intensive post-operative care. The estimated cost for this specialized surgery ranges from 1,500 to 5,000 EUR.
How it's tested
Cleft Palate 1 (CP1) DNA-Test(CP1)
Primary testDNA testEin Gentest zum Nachweis der ursächlichen Mutation im DLX6-Gen, die für die Entstehung der Gaumenspalte (CP1) verantwortlich ist.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Cleft palate 1, DLX6-related?
This is a congenital birth defect affecting the skeletal and digestive systems where the roof of the mouth, known as the palate, fails to fuse properly during embryonic development. This failure leaves an abnormal opening, formally called palatoschisis, that connects the oral cavity directly to the nasal passages. Because of this opening, food and liquids can easily pass from the mouth into the respiratory tract.
How is Cleft palate 1, DLX6-related tested?
Tests currently in our database: Cleft Palate 1 (CP1) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.