Primary ciliary dyskinesia (PCD), STK36-related(PCD)
Also known as: Primary Ciliary Dyskinesia · Immotile Cilia Syndrome · STK36-associated primary ciliary dyskinesia · Kartagener-Syndrom · Ciliary dyskinesia, primary, STK36-related
Overview
What it is
Primary ciliary dyskinesia is an inherited disorder affecting the respiratory system. It causes dysfunction in the cilia, which are tiny, hair-like structures lining the airways that normally sweep away mucus, dust, and bacteria. Without functioning cilia, the lungs cannot clear themselves, leading to chronic airway inflammation and recurrent infections.
How it presents
Symptoms typically appear in puppyhood and include a persistent moist cough, chronic nasal discharge, and frequent respiratory infections. Owners may also notice their dog has low energy, struggles with exercise, or develops recurrent pneumonia.
Treatment
There is no cure for this lifelong condition, but supportive care such as inhalations, mucus-thinning medications, and antibiotics can manage symptoms. Ongoing veterinary care is required, with lifetime treatment costs typically ranging from €3,000 to €12,000.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Primary ciliary dyskinesia (PCD), STK36-related?
Primary ciliary dyskinesia is an inherited disorder affecting the respiratory system. It causes dysfunction in the cilia, which are tiny, hair-like structures lining the airways that normally sweep away mucus, dust, and bacteria. Without functioning cilia, the lungs cannot clear themselves, leading to chronic airway inflammation and recurrent infections.
How is Primary ciliary dyskinesia (PCD), STK36-related tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.