Chromosomal structural anomaly, translocation, generic
Also known as: Chromosomale Translokation · Chromosomal translocation · Karyotype abnormality · Chromosomenanomalie · Chromosomal rearrangement · …
Overview
What it is
A chromosomal translocation is a structural genetic change where pieces of chromosomes break off and reattach to different chromosomes. This rearrangement disrupts the normal organization of genetic material, which can affect multiple organ systems, particularly the reproductive system. Because the genetic instructions are scrambled, cells may not function or divide correctly.
How it presents
Affected dogs typically appear completely healthy and normal, with the condition only becoming noticeable in adulthood when they experience infertility or produce stillborn puppies or offspring with severe birth defects.
Treatment
This genetic condition cannot be cured or treated. Costs range from 300 to 1500 EUR, which primarily covers diagnostic genetic testing, such as karyotyping, and fertility evaluations.
How it's tested
Karyotypisierung (Chromosomenanalyse)(Karyotypisierung)
Primary testDNA testDie Karyotypisierung ist eine zytogenetische Untersuchung zur Bestimmung der Chromosomenanzahl und -struktur, mit der das Fehlen eines Geschlechtschromosoms (XO-Karyotyp) direkt nachgewiesen werden kann.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Chromosomal structural anomaly, translocation, generic?
A chromosomal translocation is a structural genetic change where pieces of chromosomes break off and reattach to different chromosomes. This rearrangement disrupts the normal organization of genetic material, which can affect multiple organ systems, particularly the reproductive system. Because the genetic instructions are scrambled, cells may not function or divide correctly.
How is Chromosomal structural anomaly, translocation, generic tested?
Tests currently in our database: Karyotypisierung (Chromosomenanalyse).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.