Chondrodysplasia, SLC13A1-related
Also known as: SLC13A1 chondrodysplasia · Sulfate transporter dwarfism · SLC13A1-related dwarfism · Chondrodysplasie (SLC13A1) · Sulfate dwarfism · …
Overview
What it is
This is an inherited form of dwarfism affecting the skeletal system, specifically bone and cartilage development. It is caused by a genetic mutation that leads to a deficiency in sulfate, a compound crucial for healthy bone growth. Without enough sulfate, the dog's skeleton cannot develop to its normal size and structure.
How it presents
Owners will notice that affected puppies have significantly shorter legs compared to their body size, which becomes obvious during early puppyhood. As they grow, these dogs may also develop joint stiffness, pain, and difficulty moving comfortably.
Treatment
There is no cure for this genetic condition, so management is lifelong and focuses on pain relief, joint supplements, and physical therapy. Supportive care typically costs between 1,500 and 6,000 EUR over the dog's lifetime.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
SLC13A1-Chondrodysplasie DNA-Test(SLC13A1-CD)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis der ursächlichen Mutation im SLC13A1-Gen, die zu dieser Form des Zwergenwuchses führt.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
19 of 19 breeds
Mandatory testChinookMandated by Chinook Club of America
Mandatory testGerman Shorthaired Pointer
Mandatory testGerman Wirehaired Pointer
Mandatory testKuvasz
Mandatory testLandseer
Mandatory testPolish Lowland Sheepdog
Mandatory testTatra Shepherd Dog
RecommendedEurasier
RecommendedGerman Longhaired Pointer
RecommendedGreat Pyrenees
RecommendedGreater Swiss Mountain Dog
RecommendedMiniature American Shepherd
RecommendedNorwegian Elkhound
RecommendedPudelpointer
RecommendedSamoyed
RecommendedSpinone Italiano
OptionalAustralian Shepherd
OptionalLabrador Retriever
OptionalRhodesian Ridgeback
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Chondrodysplasia, SLC13A1-related?
This is an inherited form of dwarfism affecting the skeletal system, specifically bone and cartilage development. It is caused by a genetic mutation that leads to a deficiency in sulfate, a compound crucial for healthy bone growth. Without enough sulfate, the dog's skeleton cannot develop to its normal size and structure.
How is Chondrodysplasia, SLC13A1-related tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), SLC13A1-Chondrodysplasie DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Chinook, German Shorthaired Pointer, German Wirehaired Pointer, Kuvasz, Landseer, Polish Lowland Sheepdog, Tatra Shepherd Dog, Eurasier.