Chondrodysplasia, Labrador(CHO)
Also known as: Chondrodysplasia Labrador Retriever · ITGA10 chondrodysplasia · Disproportionate dwarfism · Zwergwuchs Labrador · Chondrodysplasia Karelian Bear Dog · …
Overview
What it is
This is an inherited skeletal disorder in Labrador Retrievers that affects the development of cartilage, which is the protective tissue cushioning the joints and guiding bone growth. Because the cartilage does not develop normally, the long bones in the legs fail to grow to their full length, resulting in a form of dwarfism. This condition is inherited in an autosomal recessive manner, meaning a puppy must inherit the mutated gene from both parents to be affected.
How it presents
Owners will typically notice that affected puppies have abnormally short, sometimes bowed legs compared to their normally proportioned bodies, starting from a few weeks of age. As the puppy grows, this skeletal mismatch can lead to early-onset joint stiffness, an abnormal gait, and reluctance to exercise.
Treatment
While the underlying skeletal structure cannot be cured, the associated joint pain and mobility issues can be managed through lifelong veterinary care, weight management, and physical therapy. Depending on the severity and whether surgical intervention is needed to support the joints, lifetime treatment costs typically range from 1,500 to 6,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
ITGA10-Chondrodysplasie DNA-Test(ITGA10-CD)
Primary testDNA testEin DNA-Test, der die ursächliche Mutation im ITGA10-Gen nachweist, um betroffene Hunde und Anlageträger für diese Form des unproportionalen Zwergwuchses zu identifizieren.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Chondrodysplasia, Labrador?
This is an inherited skeletal disorder in Labrador Retrievers that affects the development of cartilage, which is the protective tissue cushioning the joints and guiding bone growth. Because the cartilage does not develop normally, the long bones in the legs fail to grow to their full length, resulting in a form of dwarfism. This condition is inherited in an autosomal recessive manner, meaning a puppy must inherit the mutated gene from both parents to be affected.
How is Chondrodysplasia, Labrador tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), ITGA10-Chondrodysplasie DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.