Bullous pemphigoid(BP)
Also known as: Bullöses Pemphigoid · Canine bullous pemphigoid · Subepidermal blistering dermatosis · Autoimmune subepidermal blistering disease
Overview
What it is
Bullous pemphigoid is a rare autoimmune disease affecting the skin. In this condition, the dog's immune system mistakenly attacks the proteins that bond the outer layer of skin, called the epidermis, to the deeper layer underneath, known as the dermis. This microscopic separation causes the skin layers to split apart and form fluid-filled blisters.
How it presents
Owners will typically notice painful blisters that quickly rupture into deep, raw sores in the mouth, on the paw pads, and around the groin. These symptoms usually first appear in young to middle-aged dogs.
Treatment
This condition is incurable and requires lifelong management with immunosuppressive medications and close veterinary monitoring. The lifetime cost of treatment and supportive care typically ranges from €2,500 to €8,000.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Bullous pemphigoid?
Bullous pemphigoid is a rare autoimmune disease affecting the skin. In this condition, the dog's immune system mistakenly attacks the proteins that bond the outer layer of skin, called the epidermis, to the deeper layer underneath, known as the dermis. This microscopic separation causes the skin layers to split apart and form fluid-filled blisters.
How is Bullous pemphigoid tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.