Benign Familial Juvenile Epilepsy (Lagotto Romagnolo)(BFJE)
Also known as: Benign Familial Juvenile Epilepsy · Juvenile Epilepsy in Lagotto Romagnolo · LGI2-associated epilepsy · Gutartige juvenile Epilepsie · Lagotto-Epilepsie · …
Overview
What it is
This is an inherited brain disorder in Lagotto Romagnolo puppies caused by a temporary dysfunction in the central nervous system during early development. Because it is inherited in an autosomal-recessive manner, a puppy must inherit two copies of the mutated gene—one from each parent—to be affected. The condition is benign, meaning it is temporary and the brain function typically normalizes as the dog matures.
How it presents
Owners will typically notice seizures, muscle tremors, and coordination problems starting between 5 and 9 weeks of age. These symptoms usually disappear completely on their own by the time the puppy is four months old.
Treatment
The condition is highly treatable and self-limiting, meaning long-term therapy is generally not necessary. In some cases, temporary anticonvulsant medication may be prescribed to manage symptoms, with overall veterinary costs typically ranging from 150 to 600 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
BFJE DNA-Test(BFJE)
Primary testDNA testDer DNA-Test identifiziert die ursächliche Mutation im LGI2-Gen, um betroffene Hunde, Träger und mutationsfreie Tiere sicher zu identifizieren.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Benign Familial Juvenile Epilepsy (Lagotto Romagnolo)?
This is an inherited brain disorder in Lagotto Romagnolo puppies caused by a temporary dysfunction in the central nervous system during early development. Because it is inherited in an autosomal-recessive manner, a puppy must inherit two copies of the mutated gene—one from each parent—to be affected. The condition is benign, meaning it is temporary and the brain function typically normalizes as the dog matures.
How is Benign Familial Juvenile Epilepsy (Lagotto Romagnolo) tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), BFJE DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Lagotto Romagnolo.