Bardet-Biedl syndrome 2(BBS2)
Also known as: Bardet-Biedl-Syndrom Typ 2 · BBS2-related ciliopathy · Canine Bardet-Biedl syndrome · BBS2-PRA
Overview
What it is
Bardet-Biedl syndrome type 2 is an inherited systemic disorder caused by a genetic defect that impairs the function of cilia, which are tiny, antenna-like structures on the surface of cells. Because these structures are crucial for cellular communication, their malfunction damages multiple organ systems at the same time. This particularly impacts the eyes and the kidneys.
How it presents
Affected dogs typically begin to lose their vision in early adulthood due to progressive retinal degeneration. Owners may also notice their dog gaining weight easily or showing signs of kidney issues, such as drinking more water and urinating more frequently.
Treatment
There is no cure for this condition, requiring lifelong management focused on specialized diets, weight control, and supportive care for kidney complications. Ongoing treatment and monitoring typically cost between 500 and 3,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Bardet-Biedl syndrome 2?
Bardet-Biedl syndrome type 2 is an inherited systemic disorder caused by a genetic defect that impairs the function of cilia, which are tiny, antenna-like structures on the surface of cells. Because these structures are crucial for cellular communication, their malfunction damages multiple organ systems at the same time. This particularly impacts the eyes and the kidneys.
How is Bardet-Biedl syndrome 2 tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel, Feragen Komplettpaket (rassespezifisch).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.