Progressive Axonopathy(PA)
Also known as: Progressive Axonopathie · Boxer axonopathy · Hereditary progressive axonopathy · Axonopathie des Boxers · PA of Boxers · …
Overview
What it is
Progressive axonopathy is an inherited neurological disorder where the nerve fibers, known as axons, in the spinal cord gradually deteriorate. These axons act as the communication lines that transmit signals between the brain and the muscles. When they degenerate, the brain can no longer properly control the dog's movements.
How it presents
Symptoms usually appear between 1 and 6 months of age, starting with an unsteady, wobbly walk and a loss of coordination. These mobility issues progress rapidly, eventually leading to paralysis of the limbs.
Treatment
There is no cure for this progressive disease, and veterinary care is focused on diagnostic testing and supportive care, which typically costs between €500 and €2,500. Because the condition is severe and worsens quickly, humane euthanasia is often recommended to prevent suffering.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Progressive Axonopathy?
Progressive axonopathy is an inherited neurological disorder where the nerve fibers, known as axons, in the spinal cord gradually deteriorate. These axons act as the communication lines that transmit signals between the brain and the muscles. When they degenerate, the brain can no longer properly control the dog's movements.
How is Progressive Axonopathy tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.