Inborn error of hepatic metabolism
Also known as: Inborn errors of metabolism · Angeborene Leberstoffwechselstörung · Hereditary metabolic liver disease · Congenital hepatic metabolic disorder · Hepatic metabolic defect
Overview
What it is
This is a congenital metabolic disorder affecting the liver, where the organ is unable to properly process certain nutrients or filter out toxins. Because the liver cannot perform these essential chemical processes, harmful waste products build up in the bloodstream and can damage both the liver itself and the nervous system.
How it presents
Symptoms typically appear during puppyhood or adolescence and include stunted growth, vomiting, lethargy, seizures, or jaundice, which is a yellowing of the gums and skin. These signs often become more noticeable shortly after the dog eats.
Treatment
This condition is not curable and requires lifelong management, including a strict specialized diet, supportive medications, and regular veterinary checkups. The estimated cost for this ongoing care ranges from 3,000 to 12,000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Inborn error of hepatic metabolism?
This is a congenital metabolic disorder affecting the liver, where the organ is unable to properly process certain nutrients or filter out toxins. Because the liver cannot perform these essential chemical processes, harmful waste products build up in the bloodstream and can damage both the liver itself and the nervous system.
How is Inborn error of hepatic metabolism tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.