Renal amyloidosis
Also known as: Nierenamyloidose · Familial Renal Amyloidosis · Amyloidnephropathie · Familäre Amyloidose der Niere · AA Amyloidosis · …
Overview
What it is
Renal amyloidosis is a severe condition where abnormal, insoluble proteins called amyloid build up in the kidneys. Over time, these protein deposits crowd out and destroy the healthy filtering tissues of the organ. This leads to progressive kidney damage and impairs the body's ability to filter waste products from the blood.
How it presents
Owners typically notice symptoms in young to middle-aged dogs, including increased thirst and urination, weight loss, vomiting, and swelling or fluid retention. These signs reflect the gradual loss of kidney function.
Treatment
There is no cure for this progressive disease, and management focuses on lifelong supportive care, specialized diets, and medications. Diagnostic testing, such as a renal biopsy, and ongoing treatment typically cost between 2,000 and 7,500 EUR.
How it's tested
Hautbiopsie und histopathologische Untersuchung(Biopsie)
Primary testClinical examEine Hautbiopsie mit anschließender histopathologischer Untersuchung der Haarfollikel dient dem Nachweis von dysplastischen Follikeln und abnormalen Pigmentansammlungen.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Klinische und histopathologische Nierenuntersuchung(Nierenbiopsie & Labor)
Primary testClinical examDie Diagnose wird klinisch durch den Nachweis einer Proteinurie im Urin, Blutuntersuchungen und Ultraschall gestellt; die definitive Absicherung erfolgt über eine histopathologische Untersuchung einer Nierenbiopsie mittels Kongorot-Färbung.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Renal amyloidosis?
Renal amyloidosis is a severe condition where abnormal, insoluble proteins called amyloid build up in the kidneys. Over time, these protein deposits crowd out and destroy the healthy filtering tissues of the organ. This leads to progressive kidney damage and impairs the body's ability to filter waste products from the blood.
How is Renal amyloidosis tested?
Tests currently in our database: Hautbiopsie und histopathologische Untersuchung, Klinische und histopathologische Nierenuntersuchung.
Which breeds are most affected?
Most commonly affected: English Foxhound.