Retinal atrophy, cone-rod dystrophy, SPATA7-related(CRD)
Also known as: SPATA7-CRD · SPATA7 cone-rod dystrophy · SPATA7-associated progressive retinal atrophy · Cone-rod dystrophy SPATA7-related · SPATA7-PRA
Overview
What it is
This is an inherited eye disease in Standard Poodles caused by a genetic deletion in the SPATA7 gene, which leads to the progressive breakdown of the retina. The retina is the light-sensitive layer at the back of the eye, and this condition specifically damages both the cone cells, which handle daylight and color vision, and the rod cells, which handle night vision. As these photoreceptor cells degenerate, the dog's ability to see is permanently lost.
How it presents
Owners typically notice their dog bumping into objects or hesitating in both bright daylight and dim twilight, often starting from a young age. This progressive vision impairment eventually leads to complete blindness.
Treatment
There is no cure for this condition, meaning treatment is focused on supporting the dog's quality of life as they lose their sight. Lifetime management, including veterinary eye checks and safety aids for blind dogs, typically costs between 500 and 2000 EUR.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Retinal atrophy, cone-rod dystrophy, SPATA7-related?
This is an inherited eye disease in Standard Poodles caused by a genetic deletion in the SPATA7 gene, which leads to the progressive breakdown of the retina. The retina is the light-sensitive layer at the back of the eye, and this condition specifically damages both the cone cells, which handle daylight and color vision, and the rod cells, which handle night vision. As these photoreceptor cells degenerate, the dog's ability to see is permanently lost.
How is Retinal atrophy, cone-rod dystrophy, SPATA7-related tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.