Progressive rod-cone degeneration (PRCD-PRA)(PRA-prcd)
Also known as: prcd-PRA · Progressive rod-cone degeneration · Progressive Retinaatrophie prcd · PRCD-related progressive retinal atrophy · Progressive rod-cone degeneration, PRCD-related
Overview
What it is
This is an inherited eye disease where the light-sensitive cells in the retina, called rods and cones, slowly break down over time. The rods, which handle vision in dim light, degenerate first, followed by the cones, which are responsible for bright light and color vision. This gradual degeneration of the eye's sensory layer eventually leads to complete blindness.
How it presents
Owners typically first notice night blindness or difficulty navigating in the dark during early adulthood. As the disease progresses, daytime vision also deteriorates, usually leading to total blindness by middle age.
Treatment
There is currently no cure or treatment to stop this progressive vision loss. Veterinary costs generally range from 300 to 1500 EUR, which covers the initial specialist ophthalmology consultations, diagnostic testing, and supportive care to help the dog adapt.
How it's tested
PRA-prcd DNA-Test(PRA-prcd)
Primary testDNA testProgressive Retina-Atrophie (prcd-Variante). Autosomal rezessiv. Erkennt Anlageträger.
Issuing body: Optigen
Result scheme: Clear/Carrier/Affected
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
17 of 17 breeds
Mandatory testBlue Picardy SpanielMandated by Verein für französische Vorstehhunde e.V. (VBBFL)
Mandatory testBraque de l'AriègeMandated by Verein für französische Vorstehhunde e.V.
Mandatory testBraque du BourbonnaisMandated by Verein für französische Vorstehhunde e.V. (VBBFL)
Mandatory testGerman SpitzMandated by Verein für Deutsche Spitze e.V.
Mandatory testGreat SpitzMandated by Verein für Deutsche Spitze e.V.
Mandatory testJapanese SpitzMandated by Verein für Deutsche Spitze e.V.
Mandatory testLabrador RetrieverMandated by Labrador Club Deutschland e.V.
Mandatory testMiniature PoodleMandated by Deutscher Pudel-Klub e.V.
Mandatory testMittelspitzMandated by Verein für Deutsche Spitze e.V.
Mandatory testPomeranianMandated by Verein für Deutsche Spitze e.V.
Mandatory testPont-Audemer SpanielMandated by Verein für französische Vorstehhunde – VBBFL e.V.
Mandatory testPoodleMandated by Deutscher Pudel-Klub e.V.
Mandatory testSmall SpitzMandated by Verein für Deutsche Spitze e.V.
Mandatory testStandard PoodleMandated by Deutscher Pudel-Klub e.V.
Mandatory testToy PoodleMandated by Deutscher Pudel-Klub e.V.
Mandatory testVolpino ItalianoMandated by Verein für Deutsche Spitze e.V.
Mandatory testWolfspitzMandated by Verein für Deutsche Spitze e.V.
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Progressive rod-cone degeneration (PRCD-PRA)?
This is an inherited eye disease where the light-sensitive cells in the retina, called rods and cones, slowly break down over time. The rods, which handle vision in dim light, degenerate first, followed by the cones, which are responsible for bright light and color vision. This gradual degeneration of the eye's sensory layer eventually leads to complete blindness.
How is Progressive rod-cone degeneration (PRCD-PRA) tested?
Tests currently in our database: PRA-prcd DNA-Test, Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Blue Picardy Spaniel, Braque de l'Ariège, Braque du Bourbonnais, German Spitz, Great Spitz, Japanese Spitz, Labrador Retriever, Miniature Poodle.