Progressive Retinal Atrophy (prcd-PRA)(PRA)
Also known as: Progressive Rod-Cone Degeneration · gPRA prcd · Progressive Retinal Atrophy prcd · Progressive Retinal Atrophy · Progressive Retinaatrophie · …
Overview
What it is
Progressive rod-cone degeneration (prcd-PRA) is an inherited eye disease that causes the light-sensitive cells in the retina, which lines the back of the eye, to gradually break down and die. This degeneration affects both eyes and eventually leads to complete blindness. Because the retina cannot process light properly, the dog's brain stops receiving visual information.
How it presents
Owners usually first notice night blindness, where the dog hesitates or bumps into things in dim light, typically starting in early to mid-adulthood. Over months or years, this progresses to a loss of daytime vision and eventual blindness.
Treatment
There is no cure for this progressive condition, so management focuses on supportive care and helping the dog adapt to vision loss. Lifetime diagnostic monitoring and veterinary ophthalmologist consultations typically cost between 250 and 1200 EUR.
How it's tested
PRA-prcd DNA-Test(PRA-prcd)
Primary testDNA testProgressive Retina-Atrophie (prcd-Variante). Autosomal rezessiv. Erkennt Anlageträger.
Issuing body: Optigen
Result scheme: Clear/Carrier/Affected
prcd-PRA DNA-Test(prcd-PRA)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis der prcd-Mutation, die für diese Form der progressiven Retinaatrophie verantwortlich ist.
Issuing body: Optigen
Result scheme: Clear/Carrier/Affected
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Eye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
24 of 30 breeds
Mandatory testAppenzell Mountain DogMandated by Schweizer Sennenhund-Verein für Deutschland e.V.
Mandatory testBernese Mountain DogMandated by Schweizer Sennenhund-Verein für Deutschland e.V.
Mandatory testBolonka Zwetna
Mandatory testBraque du BourbonnaisMandated by Verein für französische Vorstehhunde e.V. (VBBFL)
Mandatory testCatalan Sheepdog
Mandatory testDutch ShepherdMandated by American Dutch Shepherd Association (ADSA)
Mandatory testEntlebucher Mountain DogMandated by Schweizer Sennenhund-Verein für Deutschland e.V. (SSV)
Mandatory testFlat-Coated RetrieverMandated by Deutscher Retriever Club (DRC) / VDH
Mandatory testGreat SpitzMandated by Verein für Deutsche Spitze e.V.
Mandatory testGreater Swiss Mountain DogMandated by Schweizer Sennenhund-Verein für Deutschland e.V. (SSV)
Mandatory testMaltipoo
Mandatory testPont-Audemer SpanielMandated by Verein für französische Vorstehhunde – VBBFL e.V.
Mandatory testRusskiy Toy (Shorthair)
Mandatory testSchnoodle
Mandatory testSmall SpitzMandated by Verein für Deutsche Spitze e.V.
Mandatory testYorkiepoo
RecommendedAffenpinscher
RecommendedAustralian Kelpie
RecommendedBolognese
RecommendedHavanese
RecommendedPyrenean Shepherd
RecommendedPyrenean Shepherd (Smooth-faced)
RecommendedShar-Pei
RecommendedSlovakian Wild Boar Dog
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Progressive Retinal Atrophy (prcd-PRA)?
Progressive rod-cone degeneration (prcd-PRA) is an inherited eye disease that causes the light-sensitive cells in the retina, which lines the back of the eye, to gradually break down and die. This degeneration affects both eyes and eventually leads to complete blindness. Because the retina cannot process light properly, the dog's brain stops receiving visual information.
How is Progressive Retinal Atrophy (prcd-PRA) tested?
Tests currently in our database: PRA-prcd DNA-Test, prcd-PRA DNA-Test, ECVO Augenuntersuchung (DOK), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Appenzell Mountain Dog, Bernese Mountain Dog, Bolonka Zwetna, Braque du Bourbonnais, Catalan Sheepdog, Dutch Shepherd, Entlebucher Mountain Dog, Flat-Coated Retriever.