Myelodysplastic syndrome(MDS)
Also known as: Myelodysplastisches Syndrom · Preleukemia · Myelodysplasia · Refractory anemia in dogs
Overview
What it is
Myelodysplastic syndrome (MDS) is a severe disorder of the bone marrow, which is the tissue inside bones responsible for producing blood cells. In affected dogs, the bone marrow produces abnormal, immature blood cells that fail to develop properly and cannot function. This leads to a critical shortage of healthy red blood cells, white blood cells, or platelets in the bloodstream. A bone marrow biopsy or aspirate is the essential diagnostic test used to confirm this abnormal cell development and distinguish MDS from leukemia.
How it presents
Owners may notice signs of severe weakness, pale gums, frequent infections, or tiny purple spots on the skin caused by bleeding. While this condition is most commonly diagnosed in older dogs, it can occasionally develop in younger animals.
Treatment
MDS is generally incurable and requires lifelong supportive care, such as blood transfusions and medications to stimulate cell production. Managing this condition is intensive, with typical treatment costs ranging from 2,000 to 8,000 EUR.
How it's tested
Knochenmarksaspirat und -biopsie(Knochenmarksbiopsie)
Primary testClinical examDie Diagnose des Myelodysplastischen Syndroms erfolgt über eine zytologische Untersuchung eines Knochenmarksaspirats sowie eine histologische Beurteilung einer Knochenmarksbiopsie in Kombination mit einem vollständigen Blutbild.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Myelodysplastic syndrome?
Myelodysplastic syndrome (MDS) is a severe disorder of the bone marrow, which is the tissue inside bones responsible for producing blood cells. In affected dogs, the bone marrow produces abnormal, immature blood cells that fail to develop properly and cannot function. This leads to a critical shortage of healthy red blood cells, white blood cells, or platelets in the bloodstream. A bone marrow biopsy or aspirate is the essential diagnostic test used to confirm this abnormal cell development and distinguish MDS from leukemia.
How is Myelodysplastic syndrome tested?
Tests currently in our database: Knochenmarksaspirat und -biopsie.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.