Chronic myelomonocytic leukemia(CMML)
Also known as: Chronische myelomonozytäre Leukämie · Canine CMML · Myelomonozytäre Leukämie Hund · Myeloproliferative Erkrankung Hund
Overview
What it is
Chronic myelomonocytic leukemia (CMML) is a severe, rare blood cancer originating in the bone marrow, where the body produces an uncontrolled excess of abnormal white blood cells. This overproduction crowds out healthy blood cells, impairing normal blood functions like oxygen transport and immune defense. A definitive diagnosis requires a complete blood count and a bone marrow biopsy, which is the gold standard method for identifying this condition.
How it presents
The disease typically develops gradually in older dogs. Owners may notice progressive symptoms such as lethargy, unexplained weight loss, pale gums, or an enlarged abdomen caused by swelling of the liver or spleen.
Treatment
While there is no cure, lifelong palliative chemotherapy and supportive care can help maintain the dog's quality of life. Managing this severe condition is costly, with treatment and ongoing monitoring typically ranging from 3,000 to 10,000 EUR.
How it's tested
Hämatologische Untersuchung und Knochenmarkbiopsie(CBC/BM)
Primary testClinical examDie Diagnose erfolgt über ein vollständiges Blutbild zum Nachweis einer anhaltenden Monozytose sowie eine Knochenmarkbiopsie zur Beurteilung der Myelopoese.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Chronic myelomonocytic leukemia?
Chronic myelomonocytic leukemia (CMML) is a severe, rare blood cancer originating in the bone marrow, where the body produces an uncontrolled excess of abnormal white blood cells. This overproduction crowds out healthy blood cells, impairing normal blood functions like oxygen transport and immune defense. A definitive diagnosis requires a complete blood count and a bone marrow biopsy, which is the gold standard method for identifying this condition.
How is Chronic myelomonocytic leukemia tested?
Tests currently in our database: Hämatologische Untersuchung und Knochenmarkbiopsie.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.