Degenerative Myelopathy (Bernese Mountain Dog variant) SOD1(DM-2)
Also known as: Degenerative Myelopathy Bernese Mountain Dog Type · SOD1B Degenerative Myelopathy · SOD1-B · Canine Degenerative Myelopathy SOD1B · DM SOD1B · …
Overview
What it is
This is a severe, progressive disease of the spinal cord and nervous system specifically affecting Bernese Mountain Dogs. It is caused by a genetic mutation in the SOD1 gene that leads to the gradual breakdown of the nerve pathways that send signals from the brain to the limbs. As these pathways deteriorate, the dog slowly loses the ability to coordinate its movements.
How it presents
Symptoms typically appear around 8 years of age, starting with uncoordinated movements in the hind legs and muscle wasting. Over time, this weakness slowly progresses to complete, painless paralysis.
Treatment
There is no cure for this progressive disease, and treatment is limited to supportive care such as physiotherapy and mobility aids. Lifelong management and equipment costs typically range from 1,000 to 5,000 EUR.
How it's tested
DM (SOD1) DNA-Test(DM-SOD1)
Primary testDNA testDegenerative Myelopathie (SOD1-Mutation). Unvollständig dominant; Affected zeigt nicht immer Symptome, aber Risiko bleibt.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Degenerative Myelopathy (Bernese Mountain Dog variant) SOD1?
This is a severe, progressive disease of the spinal cord and nervous system specifically affecting Bernese Mountain Dogs. It is caused by a genetic mutation in the SOD1 gene that leads to the gradual breakdown of the nerve pathways that send signals from the brain to the limbs. As these pathways deteriorate, the dog slowly loses the ability to coordinate its movements.
How is Degenerative Myelopathy (Bernese Mountain Dog variant) SOD1 tested?
Tests currently in our database: DM (SOD1) DNA-Test, Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Silken Windhound.