Cone-rod dystrophy 2 (crd2)(crd2)
Also known as: Cone-rod dystrophy 2 · crd2-PRA · Cone-rod degeneration 2 · IQCB1-PRA · Progressive retinal atrophy - crd2 · …
Overview
What it is
Cone-rod dystrophy 2 is an inherited eye disease that affects the retina, which is the light-sensitive tissue at the back of the eye. In this condition, the specialized cells called photoreceptors—specifically the cones for daylight vision and the rods for low-light vision—degenerate prematurely. This progressive breakdown leads to an irreversible loss of sight.
How it presents
Owners may first notice their puppy struggling to see or bumping into objects in bright light, with symptoms appearing as early as 10 weeks of age. The condition progresses rapidly, typically resulting in complete blindness by one year of age.
Treatment
There is no cure or treatment to stop the progression of this painless condition. Lifetime costs generally range from 300 to 1500 EUR, which covers the initial veterinary ophthalmologist diagnosis and minor home safety adaptations to help the blind dog navigate safely.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Cone-rod dystrophy 2 (crd2)?
Cone-rod dystrophy 2 is an inherited eye disease that affects the retina, which is the light-sensitive tissue at the back of the eye. In this condition, the specialized cells called photoreceptors—specifically the cones for daylight vision and the rods for low-light vision—degenerate prematurely. This progressive breakdown leads to an irreversible loss of sight.
How is Cone-rod dystrophy 2 (crd2) tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.