Progressive Retinal Atrophy (PRA), IFT122-related(PRA-IFT122)
Also known as: IFT122-related progressive retinal atrophy · IFT122-PRA · Progressive retinal atrophy IFT122-related · Progressive Retinaatrophie IFT122 · IFT122-gPRA · …
Overview
What it is
This is an inherited eye disease where the retina, which is the light-sensitive tissue at the back of the eye, gradually degenerates. Specifically, the photoreceptor cells that detect light and color slowly die off. This progressive loss of cells eventually prevents the eye from sending visual signals to the brain.
How it presents
Owners typically first notice night blindness in early to middle adulthood, with the dog hesitating to go into dark rooms or outdoors at night. Over time, this progresses to a loss of daytime vision, eventually leading to complete blindness.
Treatment
There is currently no cure for this condition, and it eventually leads to permanent blindness, though it is not painful. Management focuses on supportive care and regular veterinary eye exams, with lifetime costs typically ranging from 500 to 2000 EUR.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Progressive Retinal Atrophy (PRA), IFT122-related?
This is an inherited eye disease where the retina, which is the light-sensitive tissue at the back of the eye, gradually degenerates. Specifically, the photoreceptor cells that detect light and color slowly die off. This progressive loss of cells eventually prevents the eye from sending visual signals to the brain.
How is Progressive Retinal Atrophy (PRA), IFT122-related tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.