Progressive Retinal Atrophy, Cone-rod dystrophy 1 (American Pit Bull Terrier)(PRA-crd1)
Also known as: Cone-rod dystrophy 1 · crd1 PRA · Progressive retinal atrophy crd1 · Zapfen-Stäbchen-Dystrophie 1 · PDE6B-PRA · …
Overview
What it is
Progressive Retinal Atrophy (crd1) is an inherited eye disease that affects the retina, which is the light-sensitive layer at the back of the eye. In affected dogs, the specialized sensory cells responsible for both day vision (cones) and night vision (rods) degenerate prematurely and irreversibly. This gradual breakdown of cells eventually prevents the eye from sending visual signals to the brain.
How it presents
Owners may first notice signs of vision loss, such as bumping into objects or disorientation in low light, starting as early as 10 weeks of age. The disease progresses rapidly, typically leading to complete blindness by one to two years of age.
Treatment
There is no cure for this condition, and management focuses on supportive care and environmental adjustments to help the dog adapt to blindness. Lifetime costs generally range from 300 to 1200 EUR, primarily covering veterinary ophthalmologist visits and safety aids.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Progressive Retinal Atrophy, Cone-rod dystrophy 1 (American Pit Bull Terrier)?
Progressive Retinal Atrophy (crd1) is an inherited eye disease that affects the retina, which is the light-sensitive layer at the back of the eye. In affected dogs, the specialized sensory cells responsible for both day vision (cones) and night vision (rods) degenerate prematurely and irreversibly. This gradual breakdown of cells eventually prevents the eye from sending visual signals to the brain.
How is Progressive Retinal Atrophy, Cone-rod dystrophy 1 (American Pit Bull Terrier) tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.