Congenital stationary night blindness (CSNB), LRIT3-related(CSNB)
Also known as: Congenital Stationary Night Blindness LRIT3-related · CSNB LRIT3 · LRIT3-associated congenital stationary night blindness · LRIT3-CSNB · Congenital stationary night blindness type 2 · …
Overview
What it is
This is a congenital (present from birth) and stationary (non-progressive) disorder of the retina, which is the light-sensitive tissue at the back of the eye. It is caused by a genetic defect that disrupts how rod cells, the photoreceptors responsible for low-light vision, transmit signals to the brain. Because of this communication breakdown, the eye cannot properly process visual information in dim environments.
How it presents
Symptoms are typically noticeable starting in puppyhood, with affected dogs showing hesitation, insecurity, or disorientation in the dark or at twilight. In normal daylight conditions, their vision and behavior are completely normal.
Treatment
While this condition is lifelong and incurable, it does not worsen over time and requires no major medical intervention. Management primarily involves simple lifestyle adjustments like improved lighting, with expected lifetime costs ranging from 150 to 600 EUR.
How it's tested
LRIT3-assoziierte kongenitale stationäre Nachtblindheit (CSNB) DNA-Test(CSNB (LRIT3))
Primary testDNA testEin DNA-Test, der die ursächliche Mutation im LRIT3-Gen identifiziert, um betroffene Hunde und Anlageträger für die angeborene stationäre Nachtblindheit zu bestimmen.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Congenital stationary night blindness (CSNB), LRIT3-related?
This is a congenital (present from birth) and stationary (non-progressive) disorder of the retina, which is the light-sensitive tissue at the back of the eye. It is caused by a genetic defect that disrupts how rod cells, the photoreceptors responsible for low-light vision, transmit signals to the brain. Because of this communication breakdown, the eye cannot properly process visual information in dim environments.
How is Congenital stationary night blindness (CSNB), LRIT3-related tested?
Tests currently in our database: LRIT3-assoziierte kongenitale stationäre Nachtblindheit (CSNB) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.