Multifocal Retinopathy 1(CMR1)
Also known as: Canine Multifocal Retinopathy 1 · Multifokale Retinopathie des Hundes Typ 1 · BEST1 retinopathy · Multifocal Retinal Dysplasia · Canine Multifocal Retinopathy Type 1 · …
Overview
What it is
Multifocal Retinopathy 1 is an inherited eye condition affecting the retina, which is the light-sensitive layer at the back of the eye. It causes small, fluid-filled blisters to form beneath this layer, leading to localized areas of retinal detachment. Despite these structural changes, the overall health of the eye is rarely compromised.
How it presents
The condition typically develops in puppies between 11 and 15 weeks of age. Owners will rarely notice any symptoms, as it almost never causes pain or visible vision impairment, and is usually only diagnosed during a veterinary eye exam.
Treatment
No treatment is available or necessary for this condition because it does not affect the dog's quality of life. The only associated costs are for occasional routine veterinary eye examinations, which typically range from 100 to 500 EUR.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Canine Multifokale Retinopathie 1 (CMR1) DNA-Test(CMR1)
Primary testDNA testEin Gentest zum Nachweis der Mutation im BEST1-Gen, die für die canine multifokale Retinopathie Typ 1 verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Multifocal Retinopathy 1?
Multifocal Retinopathy 1 is an inherited eye condition affecting the retina, which is the light-sensitive layer at the back of the eye. It causes small, fluid-filled blisters to form beneath this layer, leading to localized areas of retinal detachment. Despite these structural changes, the overall health of the eye is rarely compromised.
How is Multifocal Retinopathy 1 tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK), Canine Multifokale Retinopathie 1 (CMR1) DNA-Test, Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Boerboel, Bullmastiff, Cao Fila de Sao Miguel, Presa Canario, Cane Corso.