Canine Multifocal Retinopathy 3(CMR3)
Also known as: BEST1-related retinopathy type 3 · Multifokale Retinopathie Typ 3 · Multifocal Retinopathy Lapponian Herder type
Overview
What it is
Canine Multifocal Retinopathy 3 (CMR3) is an inherited eye disorder affecting the retina, which is the light-sensitive layer of tissue at the back of the eye. It is caused by a genetic mutation that disrupts normal fluid transport within the eye, resulting in small, blister-like detachments of the retina. These localized detachments are generally stable and do not progress to full blindness.
How it presents
The condition typically develops in puppies between 11 and 16 weeks of age. Owners will rarely notice any symptoms at home, as these retinal changes are painless and generally do not impact the dog's day-to-day vision.
Treatment
There is no cure or active treatment required for this condition, as it does not cause pain or significant vision loss. Lifetime management consists of routine veterinary monitoring, with estimated costs ranging from 150 to 800 EUR.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Canine Multifocal Retinopathy 3?
Canine Multifocal Retinopathy 3 (CMR3) is an inherited eye disorder affecting the retina, which is the light-sensitive layer of tissue at the back of the eye. It is caused by a genetic mutation that disrupts normal fluid transport within the eye, resulting in small, blister-like detachments of the retina. These localized detachments are generally stable and do not progress to full blindness.
How is Canine Multifocal Retinopathy 3 tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.