Microphthalmia, isolated, with coloboma
Also known as: Microphthalmie mit Kolobom · Isolated microphthalmia with coloboma · RBP4-related microphthalmia · Microphthalmia with cyst · Zystischer Mikrophthalmus · …
Overview
What it is
This is a congenital developmental disorder of the eyes where the eyeball does not grow to its normal size, a condition known as microphthalmia. It is accompanied by coloboma, which refers to structural gaps or missing tissue in parts of the eye such as the iris or retina. Because these structures fail to fuse properly during embryonic development, the eye's ability to function is severely compromised.
How it presents
Affected puppies are born with abnormally small, deep-set eyes, which become noticeable as soon as they open their eyelids. Owners may observe signs of impaired vision or complete blindness, such as the puppy bumping into furniture or hesitating in unfamiliar surroundings.
Treatment
The condition is incurable, requiring lifelong environmental adjustments and regular veterinary monitoring to manage secondary complications. Lifetime care and supportive treatments generally cost between 1,000 and 4,000 EUR.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Microphthalmia, isolated, with coloboma?
This is a congenital developmental disorder of the eyes where the eyeball does not grow to its normal size, a condition known as microphthalmia. It is accompanied by coloboma, which refers to structural gaps or missing tissue in parts of the eye such as the iris or retina. Because these structures fail to fuse properly during embryonic development, the eye's ability to function is severely compromised.
How is Microphthalmia, isolated, with coloboma tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.