Primary Open Angle Glaucoma (POAG), ADAMTS17-related(POAG)
Also known as: Primary Open Angle Glaucoma · ADAMTS17-associated glaucoma · Primäres Offenwinkelglaukom · Grüner Star
Overview
What it is
Primary open angle glaucoma is an inherited eye disorder where fluid inside the eye cannot drain properly, causing pressure to build up. This increased pressure damages the optic nerve and retina, which are the structures responsible for sending visual information to the brain. Over time, this pressure buildup leads to progressive and irreversible vision loss.
How it presents
Symptoms typically appear between 3 and 6 years of age and include red or bloodshot eyes, dilated pupils, and signs of eye pain such as squinting or rubbing the face. Owners will also notice a progressive decline in their dog's vision, which can eventually lead to complete blindness.
Treatment
This condition is incurable and requires lifelong management with daily eye drops and regular veterinary monitoring. In some cases, surgical removal of the affected eye is necessary to relieve pain, with overall treatment costs ranging from €1,500 to €6,000.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Primary Open Angle Glaucoma (POAG), ADAMTS17-related?
Primary open angle glaucoma is an inherited eye disorder where fluid inside the eye cannot drain properly, causing pressure to build up. This increased pressure damages the optic nerve and retina, which are the structures responsible for sending visual information to the brain. Over time, this pressure buildup leads to progressive and irreversible vision loss.
How is Primary Open Angle Glaucoma (POAG), ADAMTS17-related tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Italian Greyhound, Briquet Griffon Vendéen, Grand Griffon Vendéen, Small Swiss Hound (Bernese), Small Swiss Hound (Jura).