Central Progressive Retinal Atrophy (CPRA)(CPRA)
Also known as: Central Progressive Retinal Atrophy · Retinal Pigment Epithelial Dystrophy · RPED · Zentrale progressive Retinaatrophie · Zentraler fortschreitender Netzhautschwund
Overview
What it is
Central Progressive Retinal Atrophy (CPRA) is an inherited eye disease that affects the retina, which is the light-sensitive layer at the back of the dog's eye. In this condition, the supporting cells of the retina fail to properly process waste and transport nutrients to the light-sensing cells. Over time, this metabolic failure causes these light-sensing cells to slowly deteriorate, resulting in a gradual loss of vision.
How it presents
Symptoms typically first appear between 2 and 5 years of age, with dogs showing difficulty seeing stationary objects in bright daylight. Because the central field of vision is affected first, a dog might bump into objects directly in front of them while still noticing movement to the sides.
Treatment
There is no cure for this condition, but lifelong dietary support with Vitamin E may help slow the progression of vision loss in some dogs. Managing the disease requires regular veterinary eye examinations and ongoing supplements, with lifetime costs ranging from 600 to 3000 EUR.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Central Progressive Retinal Atrophy (CPRA)?
Central Progressive Retinal Atrophy (CPRA) is an inherited eye disease that affects the retina, which is the light-sensitive layer at the back of the dog's eye. In this condition, the supporting cells of the retina fail to properly process waste and transport nutrients to the light-sensing cells. Over time, this metabolic failure causes these light-sensing cells to slowly deteriorate, resulting in a gradual loss of vision.
How is Central Progressive Retinal Atrophy (CPRA) tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK).
Which breeds are most affected?
Most commonly affected: Nova Scotia Duck Tolling Retriever, Labrador Retriever.

