Curly Coat Dry Eye Syndrome(CC)
Also known as: Congenital Keratoconjunctivitis Sicca and Ichthyosiform Dermatosis · CCSID · Rough Coat Syndrome · Keratoconjunctivitis sicca und ichthyosiforme Dermatose · CKCSID · …
Overview
What it is
This is an inherited genetic disorder that simultaneously affects a dog's eyes, skin, and coat. It is caused by a genetic mutation that disrupts the normal development of the tear glands and the outer layer of the skin. This leads to a severe lack of tear production, known as dry eye, alongside abnormal hardening of the skin cells.
How it presents
Symptoms are visible from birth, starting with an unusually rough, curly coat. As the puppy grows, they will develop painful, dry eyes, corneal ulcers, and itchy, scaly skin.
Treatment
There is no cure, meaning the dog will require lifelong, daily treatment to manage eye lubrication and skin health. The estimated lifetime cost for this intensive supportive care ranges from 5,000 to 15,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Curly Coat Dry Eye Syndrome?
This is an inherited genetic disorder that simultaneously affects a dog's eyes, skin, and coat. It is caused by a genetic mutation that disrupts the normal development of the tear glands and the outer layer of the skin. This leads to a severe lack of tear production, known as dry eye, alongside abnormal hardening of the skin cells.
How is Curly Coat Dry Eye Syndrome tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Cavalier King Charles Spaniel, Cavapoochon.