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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Alaskan Malamute we have compiled 4 mandatory and 4 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
The Alaskan Malamute has an average health profile, which is well-managed through mandatory breeding health tests. It is particularly important to screen for hip dysplasia (HD) as well as the breed-specific polyneuropathy (AMPN), a serious neurological condition for which a reliable DNA test is available. Additionally, potential eye issues must be regularly checked by a veterinarian to ensure the continued fitness of these robust working dogs.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Alaskan Malamute we track 4 mandatory tests plus 4 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 4 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Primary Open-Angle Glaucoma(POAG)
Augen und Sehvermögen
Primary open-angle glaucoma is an inherited eye disease where the natural fluid inside the eye cannot drain properly. This fluid buildup causes a gradual increase in pressure within the eyeball, which eventually damages the optic nerve, the connection between the eye and the brain. Without management, this pressure leads to permanent blindness.
Augen · Passing: CLEAR
Cataract(HC)
Augen und Sehvermögen
A cataract is a progressive clouding of the lens inside the dog's eye, which is the clear structure that focuses light onto the retina at the back of the eye. When the lens becomes cloudy or opaque, it blocks light from entering, gradually impairing the dog's vision. If left untreated, this condition can eventually lead to complete blindness in the affected eye.
Augen · Passing: CLEAR
Zinc-responsive dermatosis(ZRD)
Haut und Fell
Zinc-responsive dermatosis is a skin disorder where a dog's body cannot properly absorb or use zinc from their food, even when eating a balanced diet. This nutritional deficiency weakens the skin's protective barrier, leading to irritation and abnormal skin cell development. Because there are no genetic tests for this condition, veterinarians diagnose it using breed history, skin biopsies, and how well the dog responds to zinc therapy.
Haut
Diabetes mellitus(DM)
Hormonelles und Stoffwechsel
Diabetes mellitus is a chronic metabolic disorder affecting the endocrine system, specifically the pancreas, which fails to produce enough insulin. Insulin is a vital hormone that allows the body's cells to absorb glucose, or sugar, from the bloodstream to use as energy. Without sufficient insulin, sugar builds up in the blood while the body's cells are starved of fuel.
Koerperfluessigkeiten · Passing: Normal
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Ocular anomalies
Both parents must be CLEAR or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
4 tests are currently mandatory under the relevant breed-club regulations. The most common are Achromatopsia-3, CNGB3-related (ACHM), Ocular anomalies, Hip dysplasia (HD). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders