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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Irish Wolfhound we have compiled 2 mandatory and 8 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
The Irish Wolfhound receives a D grade because, despite having few formal genetic tests, the breed faces significant health challenges and a very short life expectancy. These giants are particularly burdened by heart conditions such as dilated cardiomyopathy (DCM), a high risk of bone cancer, and gastric dilatation-volvulus (GDV). Regular, close cardiac screening is essential for every responsible owner.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Irish Wolfhound we track 2 mandatory tests plus 8 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 8 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Gastric dilatation-volvulus(GDV)
Andere
Gastric dilatation-volvulus, commonly known as bloat, is a severe condition affecting the stomach and digestive system. It occurs when the stomach fills with gas and twists on itself, trapping the gas and blocking blood flow to vital organs. This twisting can rapidly lead to tissue damage and cardiovascular shock if not treated immediately.
Roentgen · Passing: B
Ectropion / Entropion
Augen
These are structural eyelid abnormalities affecting a dog's eyes. In cases of entropion, the eyelid rolls inward, causing the eyelashes or fur to rub painfully against the surface of the eyeball. In ectropion, the eyelid sags or rolls outward, leaving the sensitive inner lining of the eye exposed and unprotected.
Passing: CLEAR
Corneal dystrophy(CD)
Augen und Sehvermögen
Corneal dystrophy is an inherited eye disorder where abnormal, opaque materials like fats or calcium build up in the cornea, which is the clear outer layer of the eye. This accumulation typically affects both eyes and is non-inflammatory, meaning it does not cause immediate swelling or redness. Over time, these deposits can disrupt the smooth surface of the eye.
Augen · Passing: CLEAR
Cataract(HC)
Augen und Sehvermögen
A cataract is a progressive clouding of the lens inside the dog's eye, which is the clear structure that focuses light onto the retina at the back of the eye. When the lens becomes cloudy or opaque, it blocks light from entering, gradually impairing the dog's vision. If left untreated, this condition can eventually lead to complete blindness in the affected eye.
Augen · Passing: CLEAR
Cervical vertebral compressive myelopathy(CVCM)
Bewegungsapparat
Cervical vertebral compressive myelopathy, commonly known as Wobbler syndrome, is a condition affecting the spine where the spinal cord in the neck becomes pinched. This compression is caused by malformed neck vertebrae or slipping discs between the bones. Over time, the constant pressure damages the nerve pathways that carry signals from the brain to the limbs.
Roentgen · Passing: A
Elbow Dysplasia(ED)
Bewegungsapparat
Elbow dysplasia is a developmental disorder of the musculoskeletal system where the three bones forming the elbow joint do not fit together properly. This misalignment causes abnormal friction and wear on the joint cartilage, eventually leading to painful, chronic joint inflammation and arthritis. It is a complex genetic condition influenced by multiple genes.
Roentgen · Passing: 0
Dilated cardiomyopathy(DCM)
Herz und Kreislauf
Dilated cardiomyopathy (DCM) is a severe disease of the heart muscle where the heart's chambers become stretched and enlarged. This stretching thins the heart walls, making it difficult for the heart to pump blood effectively to the rest of the body. Over time, this decreased pumping ability can lead to fluid buildup in the lungs or abdomen.
Ultraschall · Passing: NORMAL
Portosystemic hepatic encephalopathy(PSS)
Stoffwechsel
This is a neurological condition caused by liver dysfunction, typically occurring when abnormal blood vessels bypass the liver. Because the liver cannot filter toxins from the bloodstream, these harmful substances build up and directly affect the brain. This lack of proper filtration leads to central nervous system dysfunction.
Passing: Normal bile acid levels
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Heart disease
Both parents must be Score < 5 on DWZRV/CC scheme or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
2 tests are currently mandatory under the relevant breed-club regulations. The most common are Hip dysplasia (HD), Heart disease. Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders