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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Tibetan Mastiff we have compiled 5 mandatory and 1 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
The Do Khyi is considered a robust, primitive breed, but due to its enormous size, it carries an increased risk of hip dysplasia (HD) and patellar luxation. Furthermore, eye conditions such as progressive retinal atrophy (PRA) and primary lens luxation (PLL) must be ruled out through consistent mandatory health tests. If you do not insist on seeing the official health screening results of the parents when purchasing a puppy, you risk facing expensive veterinary treatments and a dog that suffers from pain later on.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Tibetan Mastiff we track 5 mandatory tests plus 1 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 1 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Elbow Dysplasia(ED)
Bewegungsapparat
Elbow dysplasia is a developmental disorder of the musculoskeletal system where the three bones forming the elbow joint do not fit together properly. This misalignment causes abnormal friction and wear on the joint cartilage, eventually leading to painful, chronic joint inflammation and arthritis. It is a complex genetic condition influenced by multiple genes.
Roentgen · Passing: 0
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Progressive Retinal Atrophy (PRA)
Both parents must be Frei or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
5 tests are currently mandatory under the relevant breed-club regulations. The most common are Progressive Retinal Atrophy (PRA) (PRA), Lens luxation (PLL), Hip dysplasia (HD). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders